sexta-feira, 3 de junho de 2011

Williams Syndrome vs walking while intoxicated

Analgesic effects of drugs of this group due to a violation of prostaglandins E2 and 12, sensitizing pain receptors to bradykinin, which is considered the main mediator of pain. This drug is prescribed orally or parenterally only as analgesics, in particular, to reduce pain in the postoperative period, the pain associated with injuries, neuritis of sciatic nerve, osteoarthritis, pain associated with cancer. Stimulates the respiratory and vasomotor centers by direct and reflex (with carotid glomeruli) of the action. Caffeine has low toxicity, however, in large doses can cause agitation, insomnia, nausea. As caffeine is administered analeptic parenterally. Similar properties vitrolic rizatriptan. To reduce the use of metoclopramide vomiting. Caffeine should not be administered to vitrolic suffering from insomnia, increased mental vozbudimostno Caffeine is contraindicated in hypertension, atherosclerosis, heart zabozhpievaniyah, glaucoma. When stimulation of 5NTID-reseptors at the ends of nerve fibers that innervate the intracranial blood vessels, decreasing the allocation Substance P - neurotransmitter that excites sensory nerve endings, blood vessels constrict. By the nature of the resorptive camphor is typical analeptic: stimulates breathing and the vessel odvigatelny centers. Oil camphor solution injected under the skin. With a significant reduction blood pressure (shock, collapse) is dominated by a central action of caffeine - blood pressure rises. Psychotropic drugs is called drug drugs, the main effect of which is aimed at mental and emotional state vitrolic . NSAIDs are not effective for pain associated with diseases of internal organs (heart attack infarction, intestinal cramping, etc.). Almost only as an analgesic used metamizolnatry (analgin). Niketamid (Kordiamin) - 25% solution of nicotinic vitrolic diethylamide. As analeptics used vitrolic niketamid, camphor, caffeine. In case of overdose Bemegride causes seizures. Means used migraine Migraine attacks manifested a strong throbbing headache, often accompanied by nausea, vomiting. Preparation appointed interior and parenterally with the weakening of breathing, lowering the tone of blood vessels. vitrolic resorptive effect of camphor vitrolic its expectorant properties: provided partial bronchial glands, camphor stimulates secretion. On chemical structure is trimethylxanthine. Camphor has vitrolic and local irritating action. Cardiotonic action of caffeine also explain the activation of Ca2 + channels (ryanodine receptors) membranes sarcoplasmic reticulum of cardiomyocytes. For acute migraine attack is highly effective sumatriptan (imigran) - serotonin agonists 5NTID receptors. On the cardiovascular system of direct action has not. Solutions of camphor are used for skin treatment to prevent bedsores. Can be effective for pain associated with neoplastic lesions of bone. However metamizolnatry may cause leukopenia and even agranulocytosis. This activates the cAMP and tsGMFzavisimye protein kinase, which leads to a decrease in the level of Ca2 + and activity kiinazy myosin light chain in the cytoplasm smooth muscle. Headache in this case is connected with the extension and the pulsation of the brain and stimulation of sensory nerve receptors.
 

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